Xi’an—Janssen Pharmaceutical LTD., China
Time: 20:00-21:00, Sep 19th, 2013
Speaker: Timothy J. Ebner
Department of Neuroscience, University of Minnesota, USA
Title: Does the Cerebellum Predict the Future?
Time: 8:30-9:15, Sep 20th, 2013
Timothy Ebner is Professor and Head of the Department of Neuroscience at the University of Minnesota and holds the Pickworth Endowed Chair in Neuroscience. Dr. Ebner has published extensively on how information is represented spatially and temporally in populations of neurons in the cerebellar cortex. Using optical imaging techniques, he is interested in the spatial processing of information and synaptic plasticity in the cerebellum as well as circuit abnormalities in the spinocerebellar and episodic ataxias. During arm movements in the monkey, Dr. Ebner has studied the representation of movement parameters in cerebellar neurons, focusing on whether the cerebellum functions as an internal model of the motor apparatus.
| HT Chang Memorial Lecture
Speaker: Mu-ming Poo
Institute of Neuroscience, CAS, China
Title: Neural Plasticity: From Synapse to Cognition
Time: 16:45-17:30, Sep 22th, 2013
In 1970's, Mu-ming Poo developed a number of theoretical and experimental approaches to the study of mobility and localization of proteins in cell membranes. During the 80's, he developed novel uses of patch-clamp recording widthods in studying transmitter secretion during nerve growth and synaptogenesis. During 90's, he made major contributions to our understanding of axon guidance and synaptic plasticity. He developed a quantitative assay for growth cone responses to gradients of guidance signals and used it to show that the growth cone turning responses can be switched between chemoattraction and chemorepulsion, depending on the intracellular levels of cyclic nucleotides. He also made novel use of cell culture systems for studying activity-dependent synaptic modification and competition between co-innervating nerve terminals. He discovered that neurotrophins can cause acute modulation of synaptic efficacy, and further demonstrated that activity can trigger neurotrophin secretion from the postsynaptic cell and can regulate the synaptic action of neurotrophins. His more recent studies had also contributed to the formulation of a quantitative spike-timing dependent Hebb's rule for long-term activity-dependent synaptic plasticity.
Website: http://www.ion.ac.cn/laboratories/int.asp id=42
Speaker: Robert Desimone
McGovern Institute for Brain Research at MIT, USA
Title: the top-down control of visual processing with attention
Time: 14:30-15:15, Sep 21th, 2013
Robert Desimone studies the brain mechanisms that allow us to focus our attention on a specific task while filtering out irrelevant distractions. Our brains are constantly bombarded with sensory information. therefore the ability to distinguish relevant information from irrelevant distractions is a critical skill, one that is impaired in many brain disorders. By studying the cortex of humans and animals, Desimone has shown that when we attend to sowidthing specific, neurons representing the critical information fire in unison -- like a chorus rising above the noise -- allowing the relevant information to be “heard” more efficiently by neurons in other regions of the brain.
Speaker: Tadashi Isa
National Institute for Physiological Sciences in Okazaki, Japan
Title: Dissecting the circuit for functional recovery after neuronal damage
Time: 9:15-10:00, Sep 20th, 2013
In 1996, Tadashi Isa became a professor at the National Institute for Physiological Sciences in Okazaki. Since then, his studies are centered on the neural mechanism of saccadic eye movements and dexterous hand movements, mainly by using the non-human primate model.
He has expanded these lines of studies to the neural mechanism of functional compensation after brain and spinal cord injury. His most recent progress is that he succeeded in the pathway-selective and reversible blockade a particular pathway in the spinal cord of non-human primates with viral vectors and succeeded in affecting their dexterous hand movements. (Kinoshita et al. Nature, 2012)
Speaker: Ru-Rong Ji
Department of Anesthesiology and Neurobiology, Duke University Medical
Center, Durham, USA
Title: Immune and glial regulation of synaptic plasticity in chronic pain
Time: 14:30-15:15, Sep 20th, 2013
Dr. Ji received his PhD degree from Shanghai Institute of Physiology, Chinese Academy of Sciences. Currently he is a Distinguished Professor at the Duke University Medical Center. Before moving to Duke University, he has been a faculty at Harvard Medical School for 14 years. Dr. Ji has been doing pain research for >20 years. He is internationally well recognized for demonstrating important roles of MAP kinase signaling pathways and glial cells in the pathogenesis of chronic pain. His current research focuses on how neuroinflammation and glial activation regulate spinal cord synaptic transmission and chronic pain. ?He has contributed more than 130 peer-reviewed publications, including 26 articles in Journal of Neuroscience. He also serves as editorial board member of Neuroscience Bulletin (Associate editor), Pain, Neuroscience, and Anesthesiology.
NYU Neuroscience Institute, New York University, Langone Medical Center, USA
Title: Segmentation of information by brain rhythms
Time: 8:45-9:30, Sep 22th, 2013
|György Buzsáki is Biggs Professor of Neuroscience at the?NYU Neuroscience Institute, New York University. His primary interests are brain oscillations, mechanisms of memory, sleep and associated diseases. His main focus is “neural syntax”, i.e., how segmentation of neural information is organized by the numerous brain rhythms to support cognitive functions. His most influential work, the two-stage model of memory trace consolidation, demonstrates how the neocortex-mediated information during learning transiently modifies hippocampal networks, followed by reactivation and consolidation of these memory traces during sleep. With more than 300 papers published on these topics, he is among the top 150 most-cited neuroscientists. Buzsáki is a Fellow of the American Association for the Advancement of Science and the Academiae Europaeae and an honorary member of the Hungarian Academy of Sciences. He sits on the editorial boards of several leading neuroscience journals, including Science and Neuron. He is a co-recipient of the 2011 Brain Prize.
Speaker: Peter Jonas
Institute of Science and Technology Austria, Austria
Title: Fast-spiking, parvalbumin-expressing GABAergic interneurons: Molecular and cellular properties of a fast-signaling device
Time: 14:30-15:15, Sep 22th, 2013
Peter Jonas' work focuses on the understanding of the function of neuronal microcircuits. The human brain is comprised of approximately 10 billions of neurons, which communicate with each other at a huge number (~ 1015 ) of specialized sites. These sites of contact and communication between neurons are termed synapses. Very broadly, synapses in the brain fall into two categories: excitatory synapses releasing the transmitter glutamate and inhibitory synapses releasing the transmitter γ-aminobutyric acid (GABA). Peter Jonas made several contributions to the functional analysis of glutamatergic synapses in the hippocampus as well as to the field of GABAergic interneuron function. He pioneered the techniques of subcellular patch clamping and paired recording. He also substantially shaped the fields of presynaptic recording and interneuron function. the results were highly influential and changed our way of thinking about the mechanisms of synaptic transmission and dynamics in neuronal microcircuits.
Speaker: Jia-wei Zhou
Institute of Neuroscience, CAS, China
Title: Role of astrocytic dopamine D2 receptor in the control of neuroinflammation
Time: 8:00-8:45, Sep 21th, 2013
Jiawei Zhou obtained his PhD from the Imperial College of Science, Technology and Medicine, UK in 1996. He was a postdoctoral scientist in the Hahemman University, USA in 1996-1998, and was appointed as a Laboratory Head of the Shanghai Institute of Physiology in 1998, and then in the Institute of Biochemistry and Cell Biology, CAS. He is currently the Head of the Laboratory of Development and Degeneration of Basal Ganglia in the Institute of Neuroscience, CAS. His research interest is the molecular mechanisms underlying development and degeneration of mesencephalic dopaminergic neurons in mammals. Specific focuses are in understanding cell signaling that regulates neuroinflammation in Parkinson's disease, and transcriptional programs that determine dopaminergic neuron differentiation and migration. He has published more than 30 research papers in peer-reviewed journals including Nature, PNAS and J Neurosci.
Website: http://www.ion.ac.cn/laboratories/int.asp id=53
National Institute on Drug Dependence, Peking University
Title: Mechanisms of pathological emotional memory: from animal to human
Time: 8:45-9:30, Sep 21th, 2013
Dr. Lu received the MD degree from the North China Coal Medical University in 1989 and the PhD degree at the Institute of Mental Health of West China University of Medical Sciences in 1999. He undertook post-doctoral research at the National Laboratory of Medical Neurobiology at the Shanghai Medical School of Fudan University and then at the National Institute on Drug Abuse at the National Institutes of Health in Maryland, USA, where he continued as a research scientist. In 2005, Dr. Lu returned to Beijing and served as a director and professor at the National Institute on Drug Dependence at Peking University. Dr. Lu is the Councilor of the American Society of Neuroimmune Pharmacology, Chairman of the Chinese Society of Drug Abuse and Dependence, and Vice President of the International Chinese Association of Psychiatry. He is also the Editor-in-Chief of the Chinese Journal of Drug Dependence, an Associate Editor of Drug and Alcohol Dependence, an Academic Editor of PLoS One, and an editorial board member of the International Journal of Mental Health and Addiction and American Journal of Drug and Alcohol Abuse.
Department of Psychology and Peking-Tsinghua Center for Life Sciences, Peking University, China
Title: Visual perceptual learning and its brain mechanisms: A new perspective
Time: 15:15-16:00, Sep 22th, 2013
My lab uses psychophysical methods to study human vision, with major focus on perceptual learning and its brain mechanisms. Perceptual learning, a process in which basic sensory functions are improved through training, is a major field in sensory research. In recent years we developed novel experimental paradigms to challenge the very basic assumptions of visual perceptual learning: the retinal location specificity and feature specificity of learning, which fundamentally changed the understanding of what is being learned in perceptual learning and what brain mechanisms are underlying the learning process.