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Plenary Lecture
Public Lecture  
Speaker: 方舟子
Title: 反对学术腐败,建设学术规范
Time: 16:45, Jul.31, 201
HT Chang Memorial Lecture  
Speaker: Yuh-Nung Jan
Howard Hughes Medical Institute, USA
TitleControl of Dendrite morphogenesis
Time16:45, Jul.30, 2011
Hee-Sup Shin   Yuh Nung Jan, a theoretical physicist turned neurobiologist, has always been fascinated by the nature of intelligence. When Yuh Nung entered the California Institute of Technology as a graduate student in 1968, he fully intended to study theoretical physics. But a nagging, rather nave interest in biology, coupled with his first exposure to the field of modern biology, led Yuh Nung to switch gears. His thesis advisor, the late Max Delbrück, a winner of the 1969 Nobel Prize in Medicine or Physiology and himself a physicist turned biologist, was helpful and supportive of this career change. As a graduate student in Delbrück's laboratory, Yuh Nung studied sensory transduction of the fungus Phycomyces, and later, as a postdoctoral fellow in the Caltech laboratory of Seymour Benzer, he began studying the nervous system.
Website: www.hhmi.org/research/investigators/janyn_bio.html
Leica Lecture on Neuroscience  
Speaker: Sunney Xie
Department of Chemistry and Chemical Biology, Harvard University, UAS
Title: Life at the Single Molecule Level: Imaging and Sequencing Individual Molecules in Single Cells
Time: 8:15, Jul.30, 2011


The group was one of the first to pioneer fluorescence studies of single molecules at room temperature in early 1990s and has since made important advances in single-molecule enzymology.They are interested in the fundamental question of how conformational dynamics affects enzymatic reactions. Most important to biology, however, is the ability to record movies of molecular motions and biochemical reactions. That is particularly important in elucidating the mechanisms of macromolecular machineries. Along this line, they are studying nucleic acid enzymatic systems, including DNA replication and repair machineries with our collaborators.
Website: bernstein.harvard.edu

Plenary Lecture  
Speaker: Amara, Susan G.
University of Pittsburgh, USA
Title: A new take on uptake: biogenic amine transporters and the activation of cellular signaling pathways by amphetamines
Time: 8:00, Jul.31, 2011


Our major research efforts have focused on the structure, regulation and cellular physiology of two families of sodium-dependent neurotransmitter transporters: the biogenic amine and the excitatory amino acid carriers. The dopamine, norepinephrine and serotonin transporters (DAT, NET and SERT) are well-established targets for addictive drugs including cocaine and amphetamines, and for therapeutic antidepressants. Our work continues to use molecular genetic, electrophysiological and cell biological approaches to explore the relationships between neurotransmitter transporter structure, substrate transport, inhibitor binding and ion permeation.
Website: http://www.neurobio.pitt.edu/faculty/amara.htm

Speaker: Yves Fregnac
Unite de Neuroscience Information et Complexite, France
Title: Visual cortex: From Crystal to Smoke
Time: 14:45, Jul.31, 2011


The work developed at UNIC is based on interdisciplinary approaches, ranging from electrophysiological techniques (intracellular sharp and patch recordings, dynamic clamp in vivo and in vitro), network functional imaging (voltage sensitive dye, multiple simultaneous single unit recordings and local field potentials), and psychophysical measurements to functional databases, theoretical neuroscience and computational modelling, as well as statistical physics.
Website: www.unic.cnrs-gif.fr/people/Yves_Fr%C3%A9gnac/

Speaker: Nobutaka Hirokawa
Graduate School of Medicine, University of Tokyo, Japan
Title: Kinesin superfamily Molecular Motors,KIFs: From Intracellular Transport to Brain Development, Wiring and Learning and Memory
Time: 8:00, Aug.1, 2011
Nobutaka Hirokawa


Reseach backround: The kinesin,superfamily molecular motors(KIFs) have fundamental roles in neuronal function, plasticity, morphogenesis, and survival by transporting cargos such as synaptic vesicle precursors, neurotransmitter and neurotrophic factor receptors, and mRNAs within axons and dendrites. We have identified all 45 KIFs genes in mammals such as human and mice and have been characterizing their structure and functions. Recent our studies have begun to clarify the mechanisms of cargo selection and directional transport in subcellular compartments.Furthermore, molecular genetics has revealed unexpected roles for molecular motors in brain wiring, neuronal survival, neuronal plasticity, higher brain function, and control of central nervous system and peripheral nervous system development. Thus, molecular motor research is becoming an exciting frontier of neuroscience.
Website: http://cb.m.u-tokyo.ac.jp/profile-hirokawa.html

Speaker: Hee-Sup Shin
Korean Institute of Science and Technology, Korean
Title: Studying empathy behavior in the mouse
Time: 14:00, Jul.31, 2011
Hee-Sup Shin


He received his Ph.D. in the School of Medical Sciences, Cornell University in 1983. And He also achieved Frank Lappin Horsfall, Jr. Award of Cornell University Graduate School of Medical Science. He has received numerous honors including Frank Lappin Horsfall, Jr. Award, Cornell University Graduate School of Medical Science, Korean Academy of Science and Technology, Member,Kumho Science Award, Kumho Foundation, Hantan Life Science Award, Hantan Foundation, Award for Excellent Research Paper in Science & Technology, Most and so on. In 2006, he achieved the honor of National Honor Scientist, MOST and Best Scientist Award, MOST.
Website: http://brain.kist.re.kr/korean/viewtopic.phpp=470
Speaker: Tian-Le Xu
Shanghai Jiao Tong University School of Medicine, China
Title: Understanding structure and function of acid-sensing ion channels
Time:14:00, Aug.1, 2011


Dr. Tian-Le Xu is dean and professor of Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine. He completed his education BSc 1987; MSc 1993; PhD 1996 at Fourth Military Medical University, and did postdoc training at Department of Physiology, Kyushu University in the following years. In 1999, he was awarded CAS ‘one hundred talents’ program to start Receptor Pharmacology Laboratory at Department of Neurobiology & Biophysics (as department chair during 1999-2003), University of Science and Technology of China in Hefei. He has served as a Principal Investigator and led Laboratory of Synaptic Physiology at Institute of Neuroscience, CAS, Shanghai before he moved to the present position. His current research focuses on neuronal signaling and related neural disorders with an emphasize on the role of acid-sensing ion channels in these processes. He is serving as editorial board member for the following journals: Molecular Pain (2005-); ACS Chemical Neuroscience (2009-); and Frontiers in Pharmacology of Ion Channel and Channelopathies (2010-).
Website: www.ion.ac.cn/laboratories/int.aspid=49

Speaker: Jiang-Ning Zhou
University of Science and Technology of China, China
Title: 多受体平衡紊乱导致的CRH过度驱动与抑郁症发病的新机制
Time: 14:45, Aug.1, 2011


My laboratory pursues two independent lines of research which are funded by the Ministry of Science and Technology of China and Nature Science Foundation of China. In the first project, we are interested in how the interaction between ApoE gene and environment factors be involved in the pathogenesis of Alzheimer’s disease. In the second project, we are studying the mechanism of multiple receptors regulate the activity of corticotrophin releasing hormone neurons in hypothalamus in stress response and depression. The aim of both research lines is to find putative factors and targets for therapeutic strategies. Several experimental approaches are used in these research, including behavioral, microdialysis in free running animal, cell culture, patch clamp electrophysiology, and a variety of molecular and biochemical techniques. Our work on the human hypothalamus is carried out in collaboration with Prof. Swaab in the Netherlands Institute for Neuroscience.
Website: http://biox.ustc.edu.cn/szdw/szkxybrjh/201009/t20100917_47929.html

Speaker: Li Liu
Institute of biophysics, CAS, China
Title: Two Pairs of Neurons in CNS Control Drosophila Innate Light Preference
Time: 14:00, Jul.30, 2011


Research Interests: In response to the environmental stimuli, fruit fly-Drosophila melanogaster exhibits a diversity of behavioral activities from feeding and locomotion to cognitive processes. Using a variety of experimental approaches, ranging from behavioral to molecular, our lab seeks to study how the central nervous system translates environmental stimuli to behavior. We attempt to elucidate the structure and function of the brain in relation to the production of specific behavior in Drosophila.
Website: http://sourcedb.cas.cn/sourcedb_ibp_cas/en/eibpexport/200904/t20090403_45258.html